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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '264ba1f6c4f7426cb464ab68f49f68561b5b3ae86024505ad06ba501a30824f2' 
  AND token = '99V0xp29B6pvOT9ebERWyTMD+Gtpmdi4DzQU1Ko5Nu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}