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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefbe91e5380b4197eb10e56557ebd8e2403dd097e5100de08daf64227f55edc' 
  AND token = 'pyeNQh2fc6PXPnwgwAertoi3kvWvT9r5UCTR9JLqa04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}