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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c757d0d53f32ce59d9445f806a2743bbec96cb522a3e98150dd73b483861005' 
  AND token = 'Uvex7gk3ptjnn5gTm1CvPjT8ULUs+77NTrFScSU7SEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}