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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '582994a916a4f56d2692f4893adb1e3e1d5b6cb74bc23804a910c7e5aba00130' 
  AND token = 'lDQ9f19x1Mt/kpN6jQe30otzcfyGjuEmhm0wFuOrOb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}