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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1dbd5258e8e14d2fc377cfa98a980c7c68e89cd7f96e0f85f2174a8d0222788' 
  AND token = '1Fn/2rMRvE3xrt3+dvkoz6biTYhobpbcJaHxYXnRNWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}