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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca4cc5ef4cc17151387de21ac57b4ccb24e4fc2968eae689347991770c5eb5d' 
  AND token = 'zkhUM41FW6dv+nzArvIqOx7wth8gJFn14Gyx2OkGyKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}