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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae34ab4e91f94e1b023b627a81f14fb5804978e5dd143b0ac237872814159547' 
  AND token = 'pL0jFLgjrE8hwC39SZxVBUixQvW0XcCrc7G7R7dj4AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}