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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57aebde120eb946b94e5b169279a9b9917140767445ca8b057fe26c40720d884' 
  AND token = 'FYPPYvh9TLb2ryHYHcm8o/epw9aIT75m6b+MiLu4rrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}