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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff5841d4f12ff43de787829b8cd1f9992e9cb4f9f04960c3760010f24e30573' 
  AND token = 'M+qeMM9Ld/0vDtW0x8y+aY82NUkMMmv0Zl1kb1fxg/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}