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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7b38d2a8d62c493e6dc00747fa8a73ddbbd52678914cc11ae2d3e78d1244726' 
  AND token = 'ckYJpXzBlFmCN9oU3Ur5Z/YIlHZXNUv4crys67Rs1XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}