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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77ae473b2369751a4e0a9004c1c9a93f5986df6bdc07259ef5f5bc4c03da13d8' 
  AND token = 'cXKe80YKstIF2nu5VaWGICd472P46xB19T6MGP6S0xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}