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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd219a0d4e8524ff45b734728ee5fb63e713c9423bcb3a947249a9d724b0a8bdd' 
  AND token = 'K5rss9tj0Cgujuib151Tmcom5HzesZksm4T+aq3YwG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}