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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef9e96427768c1565e8798d4abba718705c8e2aee11a145fe082b484465b078' 
  AND token = 'HyhmDnxb9/L+NPnxcqrYr56A+rDvNnHLDAy/Jkb4NT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}