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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7efb3136a9a10eb64df4e0f470359bd0df5497e288f0bf7f596a17fdded75023' 
  AND token = 'CoCQl53STmxuaHtGKcOWDKmV5nCOVm2tdyHt3afxb+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}