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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e97b280735eaffda1f648b16fe6f35702a115aab668e2691d32615b83e48d07' 
  AND token = '8ImI47FG3ENgBtWkbsT9rZtd2Cmdi2UGDmVKK5TPQnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}