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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195c49f5befbbc78afc98bcc6670d235fba190690813773d0847b2a3fc91ccdb' 
  AND token = 'S4n20agY+blCUqJCFhaa03oIYcoyk9FrrA1adQ0+Gig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}