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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d117e26adb92c0bfbd1c69ae8614aa7fdabb43eda59cfb4ae72d1a84a1a39c6' 
  AND token = '/0hmcFou4S/85NCrPRs2A3vEMzc3QMV/3MpGWoCHIHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}