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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6671a5c820453d61382fc7077c27f3c55f1025a2712ee19a34e4f5df70b1e1' 
  AND token = 'X+nizsEXWvT3RElTix4NE8DPgweLHZ+CH/F74hJ2hHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}