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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b193ca25794ae89a49c1f8b790e02897afe0674841e88ac1e3a18d7b5a766f' 
  AND token = '6F8XVyz3qNpSVtbyzhLSLq4yClP5hTBnFtkpeUyijFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}