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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4839c2433430a9a497e8c2f7a29ba63002fbb280672a28cc8aecf20ce4e0037' 
  AND token = 'cJ0MoIGHJD9d6KERUD6hBY0bdYyu0FoQ3IIPwCE9vdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}