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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5ce6683743bb08e004b419337fb495885a9bb30e05d422cca2ebd79810dabe' 
  AND token = '+r3rIInIbN6pMSPPLQzgyyiFD4kOQjrlW+hI7i1XgRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}