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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94e5e61ead1c761b8894599fa9f4c01d28307a940629d67b2067f2cee024cda6' 
  AND token = 'MJRicc2xYycAxEac99TJhCLxCcRc04PYdDzQchbsQuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}