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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78870132f3bc01d59f213b9436eabaf161eba5009c44e0e6284c0b12583e238b' 
  AND token = 'I2Y0nb7nWES+flS9bLRWWW8walDy4DwxLnk99FZx9Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}