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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cae9871d3796f9818a1f0aff1a317f03675efd1b2c0e1bc4c0eea8ce2133b78c' 
  AND token = 'yZD1w3Ah2bUjpoIHR7ML/lQQ7ghLn8gsXwueMAQtRpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}