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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90189f0117479ccafb54e8aa5b8d7a1c6a2c0c1621a374f5bc5da8a72e918491' 
  AND token = 'gyNsKZsB/EM0CEYxeCs3bGoUIq1opRtpdFx6z+DEKzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}