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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768ac46287c789b431d8494ec5d1ae53d237e7c3bc8373e8106141541569c223' 
  AND token = 'Zrg3mZ/XX7tOfMUdSqhAh4Rdz6cC/r/z3hB5hbDi5oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}