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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7358df478196dc02ce32d03dc4e61fb32f5df50c8e4a9eaf3697d02e0f0d1223' 
  AND token = 'iOKeXYu0ZIDy0gGmwNDQzmR9kzLTWBlfDZqp58hlH9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}