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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cba8f78a1d00bc4d7aeee4768e88daaa22210f152ca5ead20dc6f87cbb481300' 
  AND token = 'tTpPN/ijas9QrCV1Z/VLL+uX7djaF/35GKn1NnH4dOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}