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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b07518559e022e390a2a928782ca5524eeb131d65a556a55be5ee94c463f6b19' 
  AND token = '+PcElhNxO9UsBEUCvx1W8HmqBmZHTpqL18qjZb8Jf+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}