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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373e08bbdfac3ee9dcc2105ead5021661a6eb4456f905aac7e3bb45a4ea38f2f' 
  AND token = '3fXP6hHjpTpfcXetmi4Ir4x9TD+DXluh8wtC2JjYD0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}