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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1341dfbfbf3b06fefb10af0200e113d40d39c0afb434f0799611fc73cf7a355c' 
  AND token = '6/zd/k1TM2wIyLtGz9mETpPV7XQ1NMNtUdUkaf6G9uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}