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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a8ba8066bb350de6d13de6d254099ad5ba1921a0bb07f747bd7a2108d6b7ad' 
  AND token = 'dpuwzaJHo7U1O/uw1CzrvIrc1b/s5A00WR5D7CS+xhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}