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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd82a5cb96c5ad5c1f8d3ece591d491f12438308b4dee72bf98d65bb4b8c18278' 
  AND token = 'msHitXaGhv5xs7XAioB6kNq87vDnMiT3chi/VDuDATw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}