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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c7d91015effb0fe99a5917a5c27083ba2cd77a06058a139b1c497f893577db' 
  AND token = 'ajzD3aWpcqKJxrsT5QXLk3nS5/tWG81JWQIzTgOZ5YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}