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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ba350f6495bccc6b5e7b6df40f4223a84ffe369bc13028a585a5b89753017d' 
  AND token = '1ZCASmVFf+reJHlryW0YQheoaORev6zNttB6xMhT2AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}