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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2d05665d31cef3ba044516bd8be7cae81e82e5a8476316c6404d5bd8c5b937' 
  AND token = 'RqZRWoO6chEemk1gw9uCaR5qmDZcUUcrUtAp+WD+1lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}