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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5beefa88d8f72775605a994ab95bff466e5e19883c81c85a5f5a756bde9daf79' 
  AND token = 'GSaB/Fks9dgfFPs7/ldMpAScp1irNw+QQ5MAig5dgXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}