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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e85bc69c2bf3fcacad9ca574cbc853d30e5701339e8adf3770582ca624d378ac' 
  AND token = 'n7NdmDtTF0+insDXtBFErxGqmyhJunHJncVXAUQJ9zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}