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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c94faeccd454c58bc6686e8558c8047448dccf4bc4f6f50b81a6cd45ba72567' 
  AND token = 'aiY/zyxybk6l/LDkxF5/gsol8hkhfykswKNII7KOVyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}