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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f342a13645a6e22c508edbe1563166435633cdf07a39cbbb7670c22cb672e07' 
  AND token = '6vrp23gV9V++HvbFU0O/Kw4f9c4pHIzssKtJtKwNaOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}