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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce881cb297c64657e5da65881ad99af9c8286490de53ed58ad764e1d7661e1ed' 
  AND token = 'CH2JG6D7cFI3hoJSUWf+TaB5Z5DMsl7shrPkKpaE6lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}