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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0caf3affd4abfa1e23df729288b84363480329565d955e9e7a08df7ffaeab15' 
  AND token = 't6ebyA/o3pqSU9UE3grY/73elUJIY74fogWJ9+Tl96I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}