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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af650726bfdae15378a90af87c6c420f17e4421c26507c3b98e5cfa0da6f328' 
  AND token = '6vjc5tjJ11RRZnv/LEr9JXFTPLkX+StygDnUmS0YboQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}