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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc87f4eb02b1226a88893f54047e97a2a3781aae72fab37bd452e3cbf6a810b8' 
  AND token = 'Bl2lsWtgeg94Gzo+TLSwrnE8mTINTZ1UHKvySsIjdpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}