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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58f224e7c8f5ed46536fcd6d0398fdb408766a08a1116eb0210a1a50daf4129f' 
  AND token = 'ywTilRL2uRJxeAdgjpC4701VCe2Np0dJ4AsvNkWfv2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}