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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b6697db31f158907d4acc90a121394db66ad4c5138e4938c0230200fec03a1' 
  AND token = 'YbpuSchLtG+eSYiFE/wap5mh5M3JvLH9csx/6vPhpPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}