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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddf3b051430f45a3d80e1564af54348083436022c3dd02ec83d4b139a73c10a' 
  AND token = 'xF5VxrJML6b9nzMEchHbLteFRPuSICZFQAFpJPpLi+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}