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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2cf50de02a076d3309d807cf9399ea2cf119040acc84da8e3575b46a03310f' 
  AND token = 'OGthSONZu78X+Qdxj+iShqszngZNpR1fNBH8pC4PxXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}