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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d16c9954d86212f53e02164a00480e18033ca45b9e10411d6d227124462e02' 
  AND token = '2D7bm7u5UeBk6fGDpKib10yAsyIm2GTHE+/t2rav6+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}