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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26454105d4a593f3b60b7f234c621767e80e69e5897363e51a6b16c0880a60cf' 
  AND token = 'AM1fQHdN2SBlSZxZyRS6dh9Y437zPuFsJ5lzhDOk+KU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}